Doctoral School of Molecular Biosciences and Biotechnology

In the Doctoral School of Molecular Biosciences and Biotechnology at the TU Graz , you conduct research as a   junior scientist in the broad fields of biochemistry, molecular biology and biotechnology. Depending on the subject area of your dissertation, you complete either a doctoral programme in technical sciences or a doctoral programme in natural sciences. You receive comprehensive and specialized technical and scientific training to enhance your communication skills. In this way, you are adequately prepared to lead research groups at academic institutions and in industry.

Dissertation

  • You conduct both basic and applied independent research with a high academic standard.
  • You work on interdisciplinary and application-oriented problems.
  • You discover and describe solutions for technical and scientific problems.
  • You publish research results in internationally renowned peer-reviewed journals and present these at international conferences.

Courses (curricular workload)

  • You learn about the molecular basis of biological processes and their application in industrial processes.
  • You take part in science days, lecture series and specialised events held at the Doctoral School.
  • You meet regularly with your dissertation supervisor as well as with other students in order to discuss the progress and preliminary results of your dissertation work.
  • You are, therefore, prepared to taken on leading positions in academic institutions and industry.

Focus Areas

  • Biochemistry
  • Molecular Biology
  • Biotechnology

Woman wearing lab clothing  working with a syringe. Photo source: Lunghammer - TU Graz

  • Duration of study: 3 years
  • Academic degree : Doktorin/Doktor der technischen Wissenschaften (Dr. techn.; translation: Doctor of Technical Sciences ) or Doktorin/Doktor der Naturwissenschaften (Dr.rer.nat.; translation: Doctor of Natural Sciences ), equivalent to the Doctor of Philosophy (PhD)
  • Languages of instruction : English and German
  • Admission requirements: see requirements for doctoral programmes
  • Curriculum Doctoral Programme in Technical Sciences (in German)
  • Curriculum Doctoral Programme in Natural Sciences (in German)
  • in German: Statuten der Doctoral School Molekulare Biowissenschaften und Biotechnologie

Astrid Weninger, student of the Doctoral School of Molecular Biosciences and Biotechnology at TU Graz. Photo source: Weninger

The program provides us with the ability to independently carry out basic and applied research on a high scientific level. The Doctoral School financially supports the participation of doctoral students at national and international conferences and training seminars. Furthermore, such events as the Doc Day encourage networking among the students. After graduation, employment opportunities are offered by academic institutions and the chemical and pharmaceutical, as well as the food, industries.

Information and Advice

  • Head of the Doctoral School Harald PICHLER Assoc.Prof. Dipl.-Ing. Dr.techn. Phone: +43 316 873 4089 harald.pichler noSpam @tugraz.at
  • Dean of Studies Mario KLIMACEK Priv.-Doz. Dipl.-Ing. Dr.nat.techn. Phone: +43 316 873 8420 mario.klimacek noSpam @tugraz.at
  • Student representative Kristina MICHL BSc MSc kristina.michl noSpam @tugraz.at
  • Student representatives: PhD Union

Admission Deadlines

Admissions to doctoral studies are possible in the current semester at any time up to a maximum of ten days before the start of the general admission period of the following semester. Admission deadlines

Further informationen on registration and admission

International degree programme applicants: admission and application deadlines

phd biotechnology in austria

The following could also be of interest

  • Other doctoral schools at TU Graz
  • Continuing education

Teaching staff and Institutes

Teaching staff.

  • Institute of Biochemistry
  • Institute of Biotechnology and Biochemical Engineering
  • Institute of Environmental Biotechnology
  • Institute of Molecular Biotechnology

Graz University of Technology Rechbauerstraße 12 8010 GRAZ AUSTRIA Phone: +43 316 873 0 Fax: +43 316 873 6009 E-Mail: info noSpam @tugraz.at www.tugraz.at Campus map Opening hours: 6 am – 8 pm

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Service points

Campus Alte Technik Rechbauerstraße 12 Phone: +43 316 873 6560 portier.alte-technik noSpam @tugraz.at

Campus Neue Technik Stremayrgasse 16 Phone: +43 316 873 6570 portier.neue-technik noSpam @tugraz.at

Campus Inffeldgasse Inffeldgasse 25D Phone: +43 316 873 6580 portier.inffeld noSpam @tugraz.at

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One of Europe's leading PhD programs in the Life Sciences

Autumn Call Opens

1 September 2024

Each year our students organize a symposium highlighting various disciplines present across our campus

Vienna BioCenter PhD Program, a Doctoral school of the University of Vienna and Medical University of Vienna in collaboration with the Gregor Mendel Institute (GMI) and Institute of Molecular Biotechnology (IMBA) of the Austrian Academy of Science, Research Institute of Molecular Pathology (IMP) and the Max Perutz Labs.

Empowering Curious Researchers

As a student at the Vienna BioCenter PhD Program you will be supervised by a top scientist and have full access to state-of-the-art facilities, thus giving you an opportunity to launch a successful scientific career. Here you will find the freedom and means to develop a brilliant PhD project. The Vienna BioCenter Campus is extremely dynamic and highly multidisciplinary with research areas ranging from molecules to populations.

phd biotechnology in austria

At the Vienna BioCenter (VBC), we want to foster a world-class scientific environment where PhD students develop and excel. The purpose of the Vienna BioCenter PhD Program is to train rigorous, independent scientists through a comprehensive training program. The program encourages students to positively contribute to the advancement of science by making and publishing important scientific discoveries. The training program will allow students to acquire scientific skills, which are important for a career in science, but also for other career paths.

Our Mission

The mission of the Vienna BioCenter PhD Program is to promote interdisciplinary research in the Life Sciences at the highest level, and to help excellent PhD students develop into tomorrow's leading scientists through a comprehensive training program. The Vienna BioCenter is a world-class scientific research environment where students and group leaders from different backgrounds interact in an inter-disciplinary, open and creative environment. By promoting the exchange of ideas, by bringing together different and often complementary disciplines, and by supporting the development and adoption of novel cutting-edge technologies, we provide outstanding opportunities for ambitious and motivated students. Enrolled students are expected to contribute to the advancement of science by making important scientific discoveries and by publishing these in international, peer-reviewed journals. Our training program educates students in all areas relevant for a career in science and provides additional opportunities to acquire skills relevant for other career paths.

Check out the positions being offered in our latest call

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14 Best universities for Biotechnology in Austria

Updated: February 29, 2024

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Below is a list of best universities in Austria ranked based on their research performance in Biotechnology. A graph of 474K citations received by 13.4K academic papers made by 14 universities in Austria was used to calculate publications' ratings, which then were adjusted for release dates and added to final scores.

We don't distinguish between undergraduate and graduate programs nor do we adjust for current majors offered. You can find information about granted degrees on a university page but always double-check with the university website.

1. Medical University of Vienna

For Biotechnology

Medical University of Vienna logo

2. University of Vienna

University of Vienna logo

3. Medical University of Graz

Medical University of Graz logo

4. Medical University of Innsbruck

Medical University of Innsbruck logo

5. University of Innsbruck

University of Innsbruck logo

6. University of Natural Resources and Applied Life Sciences, Vienna

University of Natural Resources and Applied Life Sciences, Vienna logo

7. University of Graz

University of Graz logo

8. Vienna University of Technology

Vienna University of Technology logo

9. Graz University of Technology

Graz University of Technology logo

10. University of Veterinary Medicine, Vienna

University of Veterinary Medicine, Vienna logo

11. Paracelsus Medical University

Paracelsus Medical University logo

12. University of Salzburg

University of Salzburg logo

13. Johannes Kepler University Linz

Johannes Kepler University Linz logo

14. Danube University Krems

Danube University Krems logo

The best cities to study Biotechnology in Austria based on the number of universities and their ranks are Vienna , Graz , Innsbruck , and Salzburg .

Biology subfields in Austria

PhD Programme

Training young scientists is one of the core missions of the IMP. In 1993, the IMP co-founded an international PhD programme in molecular life sciences with the University of Vienna. Today, the "Vienna BioCenter PhD Program" is one of the most prestigious international PhD programmes in biology.

phd biotechnology in austria

"Empowering curious researchers" is the motto of the Vienna BioCenter PhD Program, the programme that enables students to do research for their PhD at an IMP lab. The main priorities of this programme are the effective mentoring of PhD students and ensuring that all candidates have the support and resources they need to develop their projects.

The selection for the Vienna BioCenter PhD Program is very competitive and successful candidates are rewarded with ample resources. PhD students at the IMP enjoy access to outstanding facilities and scientific services, opportunities to do any experiment useful to support their work and a pleasant work atmosphere in a modern building. All this is offered in the frame of a training programme that has become one of Europe’s most distinguished PhD programmes in molecular biology since its establishment in 1993.

The IMP and its neighbouring institutions offer a vibrant scientific atmosphere. Lecture series and weekly seminars provide PhD students with immediate access to many of the world’s most outstanding biologists. The Vienna BioCenter community with 150 research groups is a fertile ground for stimulating encounters and a good spirit – not last socially.

Meet former and current IMP PhD Students

phd biotechnology in austria

Apply to the Vienna BioCenter PhD Program

The programme has two international calls per year and recruits approximately 15 motivated young scientists in each call (all PhD Students at IMP are recruited through the Vienna BioCenter PhD Program). Access current calls via the official website of the programme:

Vienna BioCenter PhD Program

What are Group Leaders looking for in a PhD applicant? The Vienna BioCenter PhD Program is competitive and highly selective, so passion for science and research experience will be an important pre-condition. However, there is more to a good applicant. One IMP Group Leader stated that she was looking for "PhD candidates that have curious and creative minds, are passionate about science, are easy going and communicative, are highly motivated and have endurance."

And what can you expect from the programme? The best way to convey the essence of the IMP PhD student experience is perhaps to listen to past and present PhD students – for a start, please note our testimonials below, or read the interview with the 2018 Weintraub Award laureate Annika Nichols on her experience as a PhD student at the IMP.

phd biotechnology in austria

The Vienna BioCenter is highly international with excellent service facilities supporting the scientific research done here. This is really a great place to pursue competitive science.

A flexible curriculum

The programme's curriculum is flexible and was designed for and with PhD students. The Vienna BioCenter PhD students start with a 3-week introductory course – “Prime your PhD” – which is designed to prime and facilitate the implementation and development of their research projects, specifically on this campus. Throughout their training, students (like postdocs ) present their work to the campus community at the Monday Seminars .

This weekly seminar series is a great vehicle to share knowledge and expertise between different research groups and different institutes. At the same time, the seminars are an opportunity to train PhD students in presentation skills.

Numerous seminars and journal clubs take place on a regular basis, alongside several advanced courses such as scientific writing, advanced microscopy, data analysis, and others. In addition, PhD students benefit from career development workshops.

Each student is free to choose which courses he or she wants to participate in – moreover, students are encouraged to suggest and develop new courses. In addition, the VBC PhD students organise activities such as a retreat and a symposium each year. For this, they are provided with funding, support – and a lot of freedom to develop through task planning and implementation.

Alumni: What former PhD students did

phd biotechnology in austria

Out of 140 Vienna BioCenter PhD Students that graduated after PhD research at the IMP between in the 1998-2008 decade, no less than 50 are now in Group Leader positions.

A recent survey showed very high satisfaction among alumni: virtually all survey participants see their time at the Vienna BioCenter as having been a great asset for their careers.

More information

You will find further information on the Vienna BioCenter PhD Program and the forms to apply during open call at the Vienna BioCenter training website.

https://training.vbc.ac.at/

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phd biotechnology in austria

Homepage     Career     PhD Programme

PhD Programme

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Welcome to the AIT – Austrian Institute of Technology PhD programme. Our group of around 200 PhD students plays an important role in the research profile of AIT. Gaining a doctoral degree not only is an important individual career step but also enhances the excellent research conducted at AIT. PhDs deliver innovative impulses through exploration of new scientific approaches and are important nodes in AIT’s national and international scientific networks.

AIT is an applied Research and Technology Organization (RTO), and our PhD students are involved in ongoing projects while focusing on their PhD theses. In this way they gain excellent scientific and practical experience at the same time – scientific work is linked with business aspects such as entrepreneurship, patents, and the business exploitation of concepts. Furthermore, our PhD students benefit from numerous events, seminars and networking opportunities.

All PhD theses are carried out in cooperation with national and international universities. Education and supervision are provided by both organizations, which offers optimal support for outstanding research work.

For more information about our PhD programme, please explore the links below or directly contact our PhD Coordinator.  

If you are interested in joining the programme, we encourage you to apply to one of our current vacancies.  If there are no suitable current vacancies , you may submit an “ unsolicited application ” here.

In a nutshell

  • In Austria, only universities are authorized to award doctorates. AIT is a non-university Research and Technology Organisation (RTO) . Therefore, Master studies and PhDs can only be conducted in cooperation with a national or international university.
  • AIT provides access to research infrastructure and supervision for day to day research projects, while academic supervision is provided by students’ universities.
  • Each doctoral student must ensure that they have a university supervisior.
  • AIT offers a 3 year contract to pursue research work related to your PhD, with the expectation that you complete your PhD at the end of this period.
  • Starting dates offered throughout the year, depending on project requirements.
  • The PhD’s research topic must fit within the strategic goals of AIT.
  • International applicants are encouraged to apply - more details regarding support for international applicants can be found here on the AIT page for expats

How to apply

Development, kontakt formular.

Pflichtfelder sind mit einem * markiert.

Portrait photo of Michael Jordan

Michael Jordan , MA

  • +43 664 88904319
  • +43 50550-4000
  • michael.jordan(at)ait.ac.at

Check out our open PhD positions .

Studying at the University of Innsbruck

Phd and doctoral programme.

  Deadlines and Admission periods   Admission and documents required for admission   Tuition fee   Forms   Contact & Information

PhD programmes / doctoral programmes are standard study programmes designed to further develop students’ ability to carry out independent scientific work. Building on the knowledge and skills taught in diploma and master’s programmes, they aim to educate and support the next generation of researchers and scientists. In order to be admitted to a doctoral programme, students must have completed a relevant diploma or master’s programme at a university or a university of applied sciences or an equivalent study programme. Graduates are awarded the title “Doctor” in line with the respective curriculum .

>> Full range of study programmes

Deadlines and Admission periods

Dates and Deadlines »

During the general admission period you can

  • pay the tuition and/or Austrian Students’ Union Fee (incl. insurance)

Online applications  to a PhD/Doctoral Programme can be made at any time throughout the year (applies to EEA citizens). However, the university recommends that students submit their applications during the normal admission periods in order to be able to register for lectures in time. Please be aware that a special admission period applies to non-EEA applicants (May 15th for winter semester, October 15th for summer semester).

From the start of the general admission period until the end of the extension period you can :

  • be admitted as a student of another Austrian university to also study at the University of Innsbruck ,
  • be admitted to continue a study programme at the University of Innsbruck after having paid the tuition and/or Austrian Students’ Union fee at another Austrian University
  • apply for leave of absence ( before the start of term ).

Admission and documents required for admission

EEA 1 Citizens

If you want to start a Doctoral or PhD-Programme you must apply online. Besides of personal data, also required documents are uploaded. The online application and the enrolment in person are possible all year.

If you have already completed a relevant study programme at the University of Innsbruck you can apply for admission via the online student platform LFU:online.

Documents required for the online application:

  • Notice ("Bescheid") confirming awarding of Bachelor's and Master's Degree
  • diploma or master’s programme certificate,
  • Academic Transcripts
  • Diploma Supplements
  • (if necessary) Abstract of Master's Thesis
  • curriculum vitae
  • valid passport or personal identification
  • Passport photograph
  • E-Card (if available)

Foreign-language documents require translation into German or English – if applicable with proper certification – and must be uploaded. 

Non-EEA Citizens and Stateless Persons:

If you want to start a Doctoral or PhD-Programme you must apply online. Besides of personal data, also required documents are uploaded.   The online application for the winter semester is possible to 15 May and for the summer semester to 15 October.

It is expressly pointed out that the application documents can only be processed with documents proofing the conclusion of the studies. Intermediate certificates or confirmations, temporary transcripts etc. are not accepted.

Full applications will be reviewed by the Admission Department in the order of arrival. Please take care that the processing of the applications may take some time. In the case of a positive decision, you will get a notice, which you need for enrolling.

Prospective students must enrol in person at the Admission Department with the notification of the selected study programme and the original required documents and copies thereof.

  • if necessary proof of German or English language ability  

   Information for students with a foreign school-leaving certificate can be found here .

¹ The EEA (=European Economic Area) comprises the Member States of the EU (= European Union) – Austria, Belgium, Bulgaria, Croatia, Cyprus, Czech Republic, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Latvia, Lithuania, Luxembourg, Malta, Netherlands, Poland, Portugal, Romania, Slovakia, Slovenia, Spain and Sweden – and the signatory states of the EFTA (European Free Trade Association) – Liechtenstein, Iceland and Norway.

Tuition fee

Amendments to § 91 Universities Act means that from the summer semester 2013 there are new rules governing tuition fees at the University of Innsbruck.

There are several different rules that apply to students enrolled in standard study programmes. The criteria used to decide which of these rules is to be applied are the nationality of the person, his/her residence entitlement in Austria, and any connections to Austria according to the Austrian Regulation on Eligible Groups of Persons (“ Personengruppenverordnung ”). Non-degree programme students who are enrolled in individual lectures must pay a standard tuition fee of €363.36 per semester.

All students must pay the Austrian Students’ Union fee.

Degree programme students 1 exempted from paying tuition fees for a designated period:  

  • EU/EEA citizens (automatically exempted for paying tuition fees for the regular duration of study),
  • students with permanent residency (proof required - online application ),
  • students from third countries who are deemed to have a connection to Austria according to the Austrian Regulation on Eligible Groups of Persons (“Personengruppenverordnung”) (proof required - online application ),
  • students from third countries who are neither covered by the Austrian Regulation on Eligible Groups of Persons (“Personengruppenverordnung”) nor have a student residence permit (proof required).

Students in any of the abovementioned categories who exceed the regular duration of study by more than two “tolerance semesters” must pay a tuition fee of €363.36 per semester. In individual cases a tuition fee waiver may be granted, meaning that students who have exceeded the regular duration of study by more than two “tolerance semesters” remain exempted from paying the tuition fee.

  1 Degree programme students

Degree programme students 1 from third countries

Degree programme students from third countries who are not covered by the Austrian Regulation on Eligible Groups of Persons (“ Personengruppenverordnung ”), are not subject to an international agreement and are in possession of a residence permit according to § 64 Settlement and Residence Act (NAG) must pay a tuition fee of € 726.72 starting from their first term at university. No reduction of the tuition fee will be granted to these students, even if the tuition fee is paid before the end of the extension period.

1 Degree programme students

Degree programme students 1 from Least Developed Countries

Degree programme students from least developed countries (according to the DAC List of ODA Recipients) are automatically exempted from paying the tuition fee . These students do not need to apply for an exemption. However, please be aware that any change of nationality must be communicated to the university without delay.

Non-degree programme 2 students (regardless of nationality)

Non-degree programme students admitted to attend individual lectures in scientific fields must pay a tuition fee of € 363.36 per semester, regardless of their nationality. There is no increase in this fee, even if payment is not completed before the end of the extension period.

2   Non-degree programme students

Tuition fee waivers and reimbursement

In order for tuition fees to be waived or reimbursed, students must prove that their case fulfils the relevant legal requirements (e.g. working income below the marginal earnings threshold, main person responsible for childcare) and must respect certain deadlines. Application for tuition fee waiver: by 31 October for the winter semester and by 31 March for the summer semester. Application for reimbursement: by 31 March for the winter semester and by 30 September for the summer semester. Information about grounds for granting waivers and reimbursements

Forms and information sheets

  "Meldungsblatt" registration form (enrollment, disenrollment, change of study programme)  

Applications for the tuition fee to be waived or reimbursed must be made via LFU:online :

    written confirmation from a specialist doctor  (illness) 

    formal declaration (childcare)

Leave of absence

  Leave of absence

Contact & Information

Admission Department at the University of Innsbruck       » Innrain 52d/Ground Floor 

Master's and Doctoral/PhD Programmes, Study Programmes UMIT, University Continuing Education Programme »

Admission Foreign Students »

phd biotechnology in austria

  • PhD opportunities
  • Studies & Further Education
  • PhD & Doctoral Programs
  • Our PhD Study (UN094)

Become a valued member of a network of excellent scholars

If you are interested in pursuing a Ph.D. education, look no further. On these pages we have collected all information you need to find a Ph.D. position and plan your stay at Medical University Vienna. 

phd biotechnology in austria

6 Simple Steps to your Ph.D. Education

We are looking for committed and motivated students who want to pursue a career in research and science - creative minds with vision and ideas and for the joint development of solutions that address the complex questions and problems of our society. The focus of our work is always on people, their health, and on creating a sustainable health sector for all generations with the help of science. We offer you a place at one of the largest German-speaking medical universities in the heart of Vienna. Start your scientific career and develop into an expert with us. At our university, you will find many interesting and exciting research projects. If you are interested in research and creative work on highly topical and relevant subjects – and also appreciate variety in your career – then a doctorate is the right choice for you.

The choice of doctoral programs is wide, and the decision to pursue a doctorate should be well thought out. To that end, we have created a six-step guide to help you find a doctorate that’s suitable for you.

phd biotechnology in austria

Here are some useful points to reflect on to help you decide which research area might be the best fit for your Ph.D. education:

  • What am I interested in?
  • What is my motivation to do research in this area?
  • Am I willing to work in this area for many years?
  • Do I already have a certain career goal, and if so, how does this area fit into the bigger picture?
  • Do I see myself working in academia or industry in the future?
  • Who offers the best opportunities in this research area for me?

We advise you to first note down your top three research areas and narrow the list down to two or one if you can. There are no right or wrong answers here. Try to keep an open mind and answer as honestly as possible to help you make the best decision for yourself.

phd biotechnology in austria

Points to reflect on:

  • What Ph.D. programs interest me?
  • Which of the programs align with my career goals?
  • What are my expectations for my Ph.D. education?
  •  Are there any projects I find particularly interesting? Why?

Our advice: Be curious and approach the different Ph.D. programs with an open mind. You might be surprised to find an interesting Ph.D. program you otherwise might not have considered.

Please consult our Thematic Program website for inspiration.

Step 3. Check out your opportunities

phd biotechnology in austria

Any currently open Ph.D. positions that are participating in the call for applications will be displayed here on our website. To learn more about our researchers, please visit their researcher profiles or group websites. During the application process, you can indicate a preference for up to three Ph.D. positions

phd biotechnology in austria

If you are not yet familiar with Vienna, we would like to introduce you to our hometown and briefly explain why Vienna is indeed the city of our dreams .

Vienna is not only a great place to work and study, but also a great place to live. Our coffee- house culture and food and entertainment options are world-class. We have a vibrant and dynamic arts and culture scene and are home to the Donauinselfest , the biggest free European open air music festival or the very popular Vienna Ball of Scienes . Have you ever dreamed of hitting the dance floor in a princess dress or tails and dancing the night away? If your answer is yes, then Vienna is right place for you. Where else do you have the opportunity to open a ball in your life or to waltz on a different floor every weekend during the ball season. Do not worry, every ball also has a disco floor, if classical music does not quite meet your taste. In addition, the city offers not only many architectural highlights, but also borders the Vienna Forest, one of the city's many natural leisure areas. Every summer, the banks of the Danube River and the Danube canal attract scores of people who engage in water sports or just hang out on the shore to enjoy the sunset after a long day. There are plenty of great reasons to move to Vienna, but before we give you our top 5, read how Vienna performs in an international context.

Our top 5 reasons why Vienna is one of the best places to live:

1. affordable housing

2. an affordable, modern, and well-functioning public transport network

3. one of the safest major cities in Europe

4. access to high-quality and safe public health and education systems

5. Rich cultural, leisure and sporting opportunities

6.The Viennese forest and the Danube Aupark national park  are all close to the city.

Hard facts about Vienna

Let's get to the hard facts about Vienna:

Area: 414.9 km2 with 23 districts

Population: 1.9 million

Foreigners: 30% of the population (13% EU citizens, 17% third country nationals)

Weather: Central European weather - winter cool, summer hot, often windy

General freedom of religion, majority are Catholics

6 largest city in EU, largest city in Austria

Free kindergartens and public schools

39 libraries run by the city of Vienna

18 sports halls and 20 outdoor sports facilities

phd biotechnology in austria

Visit Vienna at a Distance

We have selected different media channels for your consideration to get a better feeling for our city and experience it with all your senses.

View Vienna

  • In the Mood for Vienna

Read about Vienna 

Best city map: Tips from our Viennese youth  

The best blogs about Vienna 

  • Goodnight Vienna
  • Vienna Würstelstand (English)
  • 1000 things to do in Vienna
  • Vienna Inside

Listen to tunes about the city

Music is a big part of our cultural heritage, so it’s not surprising that there are over 3,000 tunes about Vienna. You can travel musically to Vienna by listening to the perfect song collection on Spotify compiled by the Austrian Tourist Board. Speaking of music, MedUni Vienna organizes an annual graduation ceremony for all its Ph.D. students in the beautiful performance hall of the Vienna Konzerthaus.  The Konzerthaus is, in our opinion, an appropriate place to celebrate the special moment when you’re officially awarded your Ph.D. in the presence of your family and friends.

The podcast " Tell me about Vienna "" takes you on several walks through Vienna and shares many interesting anecdotes about the city and its people. Unfortunately, the podcast is available only in German. 

Researcher destination Austria

Another motivation to move to Vienna and start your scientific career here is that Austria has been continuously investing almost 3% of GDP in the area of innovation and research for years. This puts Austria above the EU average and is considered a strong innovator among medium and small enterprises. The result is a very active and creative scientific community and many industrial research institutions that have been founded or established in Austria. Scientists and researchers benefit from e.g. facilitated residence regulations and tax advantages when moving to Austria. We recommend the brochure Researcher's Guide to AUSTRIA to get a very good overview of the Austrian research landscape.

phd biotechnology in austria

Once you decide which Ph.D. program and research project you’d like to apply to, it’s time to get all your ducks in a row. For starters, assure yourself that you meet all requirements for the application and admission process, then start preparing all the needed paperwork.

  • Check out the admission checklist for the enrollment requirements
  • Check the supporting documents information in the section about our online application tool
  • Start preparing all your application documents and convert them into PDF files if necessary
  • Ask your university for your any missing or translated transcripts (in English)
  • Contact potential referees and ask them if they’ll agree to act as your referee in a timely manner
  • Craft your motivation letter.

phd biotechnology in austria

There are two ways to apply for a doctoral position:

1. Application for open PhD positions as part of the PhD call:

  • You apply online for an open PhD position as part of a call for applications (PhD Call) and you have a choice of different positions and programmes.
  • Please note that before or during the PhD Call application process you should NOT contact supervisors.

2. Direct unsolicited application to a supervisor not participating in the PhD Call

  • You apply with an unsolicited application directly to your preferred supervisor by e-mail if they are not part of the current PhD Call.
  • The complete list of supervisors and their contact details can be found on our information webpages for the PhD program .

As mentioned earlier, you can view upcoming positions on our website. Information about the application process and deadlines can also be found on this website. To start the application process, please click on the "Open Ph.D. positons" picture on top of the website. We look forward to receiving your application within the deadlines of the current call. You may soon have the opportunity to visit our campus and meet our faculty in person.

Information on the PhD Call application and procedure can be found here . In addition, we have also created an application manual for our online tool, where you can get a first insight into the process.

Application timeline for the Ph.D. call

-Autum Call 2024/25

Call opens: 07.10-15.11.2024 Submission deadline: 15.11.2024, 23:55 CET, Austrian local time Online interview days: 09-11.12.2024 MedUni Vienna visit days: 27-29.01.2025 Beginn: right away or latest with the beginning of the semester

☼Spring Call 2025

Call opens: 15.03-25.04.2025 Submission deadline: 25.04.2025, 23:55 local Austrian time Online interview days: 14-16.05.2025 MedUni Vienna visit  days: 03.06-02.07.2025 Beginn: right away or latest with the beginning of the semester

-Autum Call 2025/26

Call opens: 15.10-30.11.2025 Submission deadline: 30.11.2025, 23:55 CET, Austrian local time Online interview days: 16-18.12.2025 MedUni Vienna visit days: 03-05.02.2026 Beginn: right away or latest with the beginning of the semester

Explanation about the online Ph.D. application

Faq about the online ph.d. call application, open call application procedure.

phd biotechnology in austria

Ph.D. Life at MedUni in Vienna

phd biotechnology in austria

Scientist:in, science fan, interested in science, crazy about science or passionate about science? It doesn't matter, we call it science positive!

We have a strong community that shares their knowledge and experiences so that others can learn from them. 

Get to know people from our community here and read about their lives and work in science. 

Podcast: Trapezfisch on Fridays

Talk to a phd ambassador.

Our PhD Ambassadors are happy to share their personal experiences with the PhD program, studying at MedUni Vienna and living in Vienna in an online conversation. For this purpose, we need your first name and an e-mail address to make an appointment with you. Please note that they cannot give you advice or information about the application process. For practical questions about the application process, please contact our PhD coordinator via email and arrange an online appointment if needed.

In general, we do not offer study guidance, but we would like to give PhD candidates the opportunity to get a clear picture of what their everyday life as a PhD student at MedUni Vienna might look like.

Please note, all displayed times are in Austrian local time .

Attention! For the current PhD Call all PhD Ambassador appointments are already booked. New appointments will be released with the start of the application period of the next PhD Call. We kindly ask for your patience.

Our university

phd biotechnology in austria

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Data protection

Our campus is located in the middle of Vienna's ninth district and consists of several buildings in the immediate vicinity of our Rectorate. The Rectorate building is directly connected to the AKH (General Hospital). Our university houses 30 university hospitals and two clinical institutes, as well as 13 medical theory centers and numerous highly specialized laboratories . Each of our buildings is easy to reach by public transport or by bike. There are countless opportunities to buy food and drink on campus, including two canteens, a supermarket, and a MedUni Shop with an adjoining café. Parents can have their children looked after in one of our kindergartens. The Medical University of Vienna has been closely connected to the district and its people for centuries and therefore makes its unique collection of teaching materials, models, and instruments available to the public in the Josephinum . The Josephinum was founded in the 17th century as a medical-surgical academy to train military doctors for the Austrian army and is still part of the Medical University. The ninth district is a popular residential area in a central location with green spaces, and a wide range of restaurants, cafes, bars, parks, and sports clubs. 

We are always evolving, and so is our campus! Over the next five years, our campus will grow by two more buildings. In addition to the new Eric Kandl Building for Precision Medicine and the Research Centre for Translational Medicine and Therapies , we are also building a state-of-the-art new campus in Mariannengasse . We are already looking forward to welcoming many of our Ph.D. students on the new campus in a few years’ time. Here you can take a look at the new campus and the status of the construction project.

Our campus continues to grow with us and, as a result, has many faces.

phd biotechnology in austria

Employee benefits for Ph.D. students

As a Ph.D. student and employee at MedUni Vienna you recieve a variety of benefits.

Employment during the PhD studies

Employment as a Ph.D. student at MedUni Vienna is subject to the regulations of the collective agreement for university employees. You are entitled to a payment regulated by the collective agreement. In addition to twelve annual paychecks, you’re entitled to special payments on March 15, June 15, September 15, and November 15 of each year in the amount of half the salary due for the month of payment. You are entitled to a paid vacation of 25 working days per year.

Health, accident and pension insurance

As an employee of MedUni Vienna, you are subject to statutory health, accident and pension insurance for the entire duration of your employment.

Company pension scheme

After 24 months of an uninterrupted employment relationship, the University pays a monthly amount into the pension fund for each employee.

Flexible working hours

Ph.D. students are free to arrange their working hours according to the regulations of the collective agreement and in coordination with their superiors.

Advanced training and career counseling

We offer our employees personal career counseling and support their personal development through internal training and continuing education opportunities. In addition, our Alumni Club’s mentoring program is also available to Ph.D. students.

Residence apartment when applying for a visa

New employees who need to apply for a residency permit or visa in Austria have the opportunity to apply for an apartment on campus. It’s important to know that the allocation of a residential apartment is subject to availability and can’t be granted. The rental period is limited to 6 months for approved tenants.

Employees of the Medical University of Vienna have various options for childcare near their workplace: the Martha Wolf Kindergarten in the University Dental Clinic, a public and state-run kindergarten at Währinger Gürtel 16, and the AKH company kindergarten of the Kinderfreunde Wien at Spitalgasse 23, which accepts exclusively or favors the children of our employees.

Our Family Service unit advises and supports MedUni Vienna staff and students on matters relating to balancing work and family responsibilities, planning time off, returning to work after maternity leave, childcare solutions, and supporting relatives that require nursing care, etc.

Food and beverage facilities

Depending on their place of employment, MedUni Vienna employees have access to the AKH staff restaurant and the canteen in the University Dental Clinic. With your ID card, you have access to both facilities. A supermarket is located in the entrance hall of the AKH and is open every day of the week during normal opening hours. In addition, there are numerous pubs and stores around the campus.

Language courses

MedUni Vienna offers free English courses and training on campus, which can be booked on the intranet. In addition, we have an agreement with the University of Vienna that our employees can book any language course at a reduced rate.

Sports offer

Our university is home to several sports teams, such as the Serpents, our own football and basketball team. Furthermore, a broad selection of sports courses can be booked at the University Sports Institute Vienna (USI) at favorable rates. One of the sports facility of the USI is located just across the street from the MedUni Vienna Campus. Many of our employees are active runners and regularly represent our university at running events.

Employee discounts

As an employee you can benefit from a large number of special conditions organized by the works councils, such as price reductions at pharmacies and cultural events, more favorable terms at banks, etc..

Employee events

The university organizes several employee events each year such as graduation celebration and Christmas party.

Contact us!

We have collected all information about our PhD studies for you in our FAQ section . Please contact us directly by Email for any questions left unanswered and make an appointment with us. We will be pleased to provide you with information on any arising questions from recruiting to details about the complete academic calendar.

Our office is located in the Study Departement Building of the Medical University Vienna at the following address :

Währinger Straße 25a A-1090 Vienna, Austria

Contact for general inquiries

Dieter Breitenbaum Vesna Dominkovic

P: +43 (0)1 40160-21029 P: +43 (0)1 40160-21030

Contact for PhD Call recruiting 

Stephanie Danzinger P: +43 (0)1 40160-21033

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phd biotechnology in austria

  • Research at Vienna BioCenter
  • Research Entities
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phd biotechnology in austria

  • Companies at Vienna BioCenter
  • Ablevia Biotech
  • ADvantage Therapeutics
  • Affiris CVD GmbH
  • aitiologic GmbH
  • BioNTech R&D Austria
  • bit.bio discovery GmbH
  • CALYXHA Biotechnologies
  • G.ST Antivirals
  • HeartBeat.bio AG
  • HOOKIPA Pharma Inc.
  • Miti Biosystems
  • MyeloPro Diagnostics and Research GmbH
  • Myllia Biotechnology
  • Pregenerate
  • proxygen GmbH
  • QUANTRO Therapeutics
  • Thermo Fisher Scientific
  • THT Biomaterials GmbH
  • Tridem Bioscience
  • X4 Pharmaceuticals
  • YGION Biomedical GmbH
  • LabConsulting
  • IG StartUP Solutions GmbH

phd biotechnology in austria

  • Open Positions (current)
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phd biotechnology in austria

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Open Positions

The Campus. The Vienna BioCenter is a top biology research center in Europe conducting innovative research in all areas of the life sciences.

The Areas. The wide range of expertise, from biophysics and structural biology to cell biology and evolution, combined with a plethora of model systems, ensures diversity and interdisciplinarity.

The Research. Purely curiosity-driven research is highly valued and encouraged. A focus on basic biomedical research and mechanisms of disease, laying the groundwork for future solutions to global health problems.

The Infrastructure. Cutting-edge research infrastructure enables innovative research and provides a competitive locational advantage to all researchers on campus.

The City. Located in the city consistently ranked #1 in the Mercer Quality of Living Ranking, the Vienna BioCenter offers some of the best research opportunities in Europe and has become a magnet for inquisitive and ambitious scientists from all over the world.

The different entities at Vienna BioCenter offer career opportunities at various stages, both in science, science support and administration. See the full list of job opportunities on campus below.

phd biotechnology in austria

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University of Vienna - Main page

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Doctoral/PhD Programmes at the University of Vienna

Law/interdisciplinary legal studies.

phd biotechnology in austria

PhD in Molecular Biosciences & Biotechnology (PhD) (English & German) Graz University of Technology Graz

Degree: PhD in Molecular Biosciences & Biotechnology (PhD) (English & German)
Program Language: English
Admission Semester: Spring (March)Fall (October)
Start Date: May Intake
Program Duration: (3 yrs) 6 semesters
Semester Tuition Fees: 727 Euro
Other Fees: The tuition fees reflected above is for non-EU foreign nationals. In case of extension, extra fees will be charged. Please pay attention to the acceptance letter for actual amounts to be paid.
Cost of living: 800 - 1000 Euros per month
Job opportunities: Part-time jobs for students are competitive throughout the city.These part-time jobs usually pay from 300 to 500 euros depending on the type of work.
Funding opportunities within the university: Universities usually offer part-time opportunities to students who constantly excel academically.

Program details

Educational organisation: Graz University of Technology
Study abroad: Opportunity Available
Internships: Opportunity Available
Form of assessment: GPA Grade
ECTS credits: Each course in the program (Electives & Prerequisites) commands a certain amount of credit points.
Program objectives: Molecular Biosciences & Biotechnology (PhD) (English & German)

Minimum cost of living

Accomodation: 150 - 400 Euro / month
Food: 250 Euro / month
Cost of living: 800 Euro / month
Transportation: 30 - 50 Euro / month

Requirements

Language requirements: English Proficiency & German Proficiency
Academic requirements: Master's Degree & Transcript
Documents:

1. Master's Degree & Transcript

2. Evidence of English Language Proficiency (if applicable)

3. Evidence of German Language Proficiency (if applicable)

4. Passport Copy

Arrival support: Support Available - Provided by the university
Services and support for international students: Support Available - Provided by the university
Accomodation

*Off-Campus options available

*On-Campus options available

PhD

About Graz University of Technology:

Established in 1811 ,  The TU Graz is a modern, future-oriented educational and research institution with a distinctive international profile. It  is located in the centre of Graz, the second biggest city in Austria. With eight institutions of higher education, Graz is a real student city and is regarded as one of the cities of central Europe and the European Union with the highest quality of life.  TU Graz  offers bachelor’s, master’s, teacher training and doctoral programmes as well as postgraduate programmes.

About Austria:

Austria, largely mountainous landlocked country of South-Central Europe and is a great place for future international students like you. It has very affordable tuition fees and The quality of life is very high.

About the city:

Graz is the capital of Styria and Austria's second largest city. It   is a university town offering lots of different things to suit any taste: Night life and culture, award-winning restaurants and student bars, a vibrant city centre and lots of green spaces, history and modern life.

We have 5 PhD Projects, Programmes & Scholarships in Austria

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PhD Projects, Programmes & Scholarships in Austria

Phd position: calcium channels in congenital stationary night blindness, phd research project.

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

Funded PhD Project (Students Worldwide)

This project has funding attached, subject to eligibility criteria. Applications for the project are welcome from all suitably qualified candidates, but its funding may be restricted to a limited set of nationalities. You should check the project and department details for more information.

PhD positions in the field of molecular medicine, age-related diseases, immunology, molecular and lipid metabolism, cardiovascular research and biostatistics

Funded phd programme (students worldwide).

Some or all of the PhD opportunities in this programme have funding attached. Applications for this programme are welcome from suitably qualified candidates worldwide. Funding may only be available to a limited set of nationalities and you should read the full programme details for further information.

Austria PhD Programme

An Austrian PhD usually takes 3-4 years. Most students complete their projects within broader PhD programmes incorporating a curriculum of courses and training worth a certain number of ECTS credits as well as research towards an original thesis. This will be presented for a public examination by two academic experts. Most programmes are delivered in German, but some universities offer English-language teaching.

15 fully funded PhD positions in molecular technologies and systems medicine

Fully funded phd positions in astronomy, biology, computer science, chemistry & materials, data science & scientific computing, earth science, mathematics, neuroscience, and physics, international phd programme.

International PhD programs are often designed for international students. Your PhD will usually be delivered in English, though some opportunities to gain and use additional language skills might also be available. Students may propose their own PhD topics or apply for advertised projects.

Fully-funded PhD Positions in the Life Sciences/Molecular Biosciences

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PhD Position (m/f/d) "A Bioinformatics Approach to Analyzing Epistatic Interactions in Enzymes using Long-read Sequencing Data"

The Institute of Biomedical Informatics at Graz University of Technology (TU Graz) is seeking a highly motivated PhD candidate to join a research project in the field of enzyme engineering.This

Coordinator

answering the big questions of the future. Around 7,500 of them do research and teaching, around 2,900 work in administration and organisation. We are looking for a/an Coordinator 8556 Molecular Biology

Junior Group Leader Position at IMBA - Institute of Molecular Biotechnology

topics. IMBA invites applications for two group leader positions as part of an open search in the life sciences. Applications from researchers in areas related to germline biology , mobile genetic elements

PhD position: In the area of sustainable production – green chemistry

be fine: Biocatalysis Biochemistry Structural biology Enzymology Molecular biology Instrumental analytics (HPLC, GC, NMR, MS etc.) Bioinformatics You should enjoy the work in an international

Postdoc: deep learning for super-resolution microscopy

-resolution microscopy methods for structural cell biology . In a WWTF-funded project we will develop a new deep learning-based approach to reconstruct a movie of a cellular process from tens of thousands

Postdoc: development of a novel MINFLUX microscope

useful for biological discovery. You should hold a PhD degree in physics or engineering and should have a strong background in optics and developing complex microscope hardware. Experience building

Senior Scientist (Doctorate/ PhD )

24 May 2024 Job Information Organisation/Company University of Innsbruck Department Faculty of Biology Research Field Biological sciences Researcher Profile Recognised Researcher (R2) Country

University assistant predoctoral

Biotechnology" research group (Prof. Dr. Sergey B. Zotchev) within the Department of Pharmaceutical Sciences has a vacancy for a University Assistent praedoc ( PhD ) to investigate bacteria isolated from various

Academic Affairs Manager (m/w/d)

science and education and a good understanding of the academic system and the life sciences field. PhD in biology , biomedical sciences or related field and/or MSc/MA in education, public administration

Doctoral School in Microbiology and Environmental Science at the Centre supports PhD students in the finishing phase of their dissertation project through short-term finishing contracts. These employments

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Navigating from Phenotypic Analysis to Genomic Selection in Plant Breeding

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Online Learning Resources in Plant Breeding

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Erasmus Mundus European Master in Plant Breeding

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Doctoral programme AgriGenomics

Management and administration, addresses & contact, h97100 institute of biotechnology in plant production.

IFA, Gebäude 1 Konrad-Lorenz-Straße 20 3430 Tulln an der Donau

phd biotechnology in austria

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25 PhD jobs in Austria

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  • PhD positions in Vienna (14)
  • PhD positions in Villach (5)
  • PhD positions in Graz (3)
  • PhD positions in Innsbruck (1)
  • PhD positions in Krems (1)
  • PhD positions in St. Pölten (1)

Other countries

  • PhD positions in Belgium (195)
  • PhD positions in Netherlands (126)
  • PhD positions in Germany (54)
  • PhD positions in Switzerland (39)
  • PhD positions in Sweden (32)
  • PhD positions in Norway (29)
  • PhD positions in Luxembourg (24)
  • PhD positions in Finland (19)
  • PhD positions in France (18)
  • PhD positions in Israel (5)

Search results (25)

...

Junior Scientist (m/f/d) for site-specific channel modelling for 6G (Including a PhD Thesis)

Within our Center for Digital Safety & Security the research field Enabling Digital Technologies is leading in applied 5G and beyond research of advanced reliable wireless joint communication and sensing systems for time sensitive use cases in the...

...

PhD student (f/m/d) – computational genomics and liquid biopsies

Location: ViennaResearch group:  Sabine Taschner-Mandl GroupWorking hours: full-timeAre you looking to apply your bioinformatic skills to patient single cell data and contribute to science that makes a difference? Then this project is for you!For ...

PhD student (f/m/d) – Deep Learning/Computer Vision/Computational Biology for Bioimage Analysis

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phd biotechnology in austria

Europe: 20+ fully-funded PhD positions

Discover a wide range of courses and programs at prestigious universities across Europe in disciplines such as chemistry, biological sciences, biochemistry, biotechnology, engineering, molecular biology, medical sciences, agricultural sciences, soil science, environmental science, water science, physics,  mathematics, geosciences, computer science, industrial engineering, downstream processing, and more. Below is a list of schools offering the positions as well as direct links to the posts in the EURAXESS portal.

Here is a list of leading institutions providing these opportunities:

  • Karlsruhe Institute of Technology 
  • Medical University of Vienna
  • Institute of Haematology and Transfusion Medicine 
  • University of Bergen 
  • Basque Center for Macromolecular Design and Engineering POLYMAT Fundazioa
  • Université de Liège
  • Inserm U1297
  • Università Della Calabria 
  • Austrian Centre of Industrial Biotechnology (ACIB GmbH)
  • Lund University 
  • University of Salerno
  • University of Southern Denmark 
  • iBET - Instituto de Biologia Experimental e Tecnológica 
  • INSA Rouen Normandie 
  • Hasselt University 
  • Institute of Agrophysics of Polish Academy of Sciences
  • University of Modena and Reggio Emilia 
  • University of Iceland Science Institute  

Seize the opportunity to advance your academic and research career. Apply now for doctoral (PhD) positions at these esteemed institutions:

PhD Student in Characterization and Recovery of Bionanoparticles for Vaccine Delivery and Gene Therapy, Karlsruhe Institute of Technology (Germany)

PhD Student in the Huppa Lab at the Medical University of Vienna, Medical University of Vienna (Austria)

PhD Student in Molecular Biology, Oncology and Hematology, Institute of Haematology and Transfusion Medicine (Poland)

PhD Student in Causal Decision Making, University of Bergen (Norway) 

PhD Fellowship in Applied Chemistry and Polymeric Materials, Basque Center for Macromolecular Design and Engineering POLYMAT Fundazioa (Spain)

PhD Student in Characterization of thermo-hydro-mechanical properties of longwall goaf for geothermal energy storage in abandoned coal mines, Université de Liège (Belgium)

PhD Student in urinary cytokines for the early detection and outcome assessment of kidney injury, Inserm U1297 (Spain)

PhD Student in MetacMed - Acoustic and mechanical metamaterials for biomedical and energy harvesting applications, Università Della Calabria (Italy)

PhD Fellow in Wind Modeling, UiT The Arctic University of Norway (Norway) 

PhD Fellow in Geodynamics and Surface Processes, University of Bergen (Norway)

PhD Student in Separation and purification of bionanoparticles by convective material and 3D-printed material, Austrian Centre of Industrial Biotechnology (ACIB GmbH) (Austria)

PhD Student in Synchrotron Methods and Applications in Sweden, Lund University (Sweden)

PhD Student in Industrial Engineering (chemical engineering, mechanical engineering, electronic engineering) - University of Salerno (Italy) 

PhD Student in Model-based prediction of bionanoparticle separation by continuous ultracentrifugation and convective chromatography, Austrian Centre of Industrial Biotechnology (ACIB GmbH) (Austria)

PhD Student in LLM-assisted Multirobot Mission Planning and Control, University of Southern Denmark (Denmark)

PhD Student in Area of Natural Bioactives & Nutraceuticals, iBET - Instituto de Biologia Experimental e Tecnológica (Portugal) 

PhD Student in Electrochemical Gold-Catalysed Processes, INSA Rouen Normandie (France)

PhD Student quantum mechanical modelling of polymers, Hasselt University (Belgium)

PhD Student in legume-based diversification of cereal cropping systems, IRTA (Spain)

PhD Student in Splash phenomenon as a mechanism of transportation of soil bacteria, Institute of Agrophysics of Polish Academy of Sciences (Poland)

PhD Research Fellow in applied and computational mathematics, University of Bergen (Norway)

PhD Student in Palynology, University of Modena and Reggio Emilia (Italy)

PhD Student in AI-modelling of Powerful Microwaves in Fusion Plasmas, University of Southern Denmark (Denmark) 

PhD Student in personalized medicine in chronic kidney disease, Inserm U1297 (France)

PhD Student in method development and simulation of solid / liquid interfaces,

University of Iceland Science Institute (Iceland)

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BASF and the University of Graz develop fundamentally new computer-assisted model to optimize efficiency of biocatalytic production processes

  • Computer model enables a new understanding of enzymatic catalysis
  • Production processes can be scaled up faster from the lab to industrial manufacturing
  • Greater sustainability in biocatalysis thanks to lowered costs and resource consumption

Numerous factors influence the efficiency of the enzymes used to produce chemicals. Finding the optimal reaction conditions therefore requires significant time and resources. Researchers from BASF, the Austrian Research Centre of Industrial Biotechnology (acib) and the University of Graz in Austria have co-developed a fundamentally new computer-assisted model that can improve enzyme performance and enable new biocatalytic production processes to be scaled up faster from the lab to industrial manufacturing.

Enzymes are proteins that perform many functions in the human body and all other organisms. They are biological catalysts that speed up chemical reactions. Enzymes are involved in almost all metabolic processes in the body, such as the digestion of food or the formation of cells and tissue. The chemical industry also uses enzymes as biocatalysts in production processes. BASF uses them to make products such as vitamins, flavorings or ingredients for cosmetics and detergents.

But enzymes are very sensitive and stop working properly if, for example, the temperature is too high. “They are then no longer correctly folded and lose their three-dimensional structure, which means no further catalytic reactions can take place in their active center,” explains Dr. Stefan Seemayer, global head of computational protein engineering at BASF. However, enzymes also cannot function optimally when temperatures are too low, producing lower volumes of the desired product.

The activity of the biocatalysts can also be influenced by substances contained in the reaction medium, such as solvents. “We need solvents so that the enzymes can quickly produce large amounts of the desired end product from the starting materials, for example, fats,” says Seemayer. Without solvents, the enzymes are unable to fully access the substances and transform them into other materials. But if the solvent concentration or the temperature are too high, the enzymes lose their structure and stop being active. On the other hand, if the concentration or the temperature are too low, this can reduce product output.

Finding an optimal combination of temperature and solvent concentration

“In order to get the largest possible amounts of the desired product, we need to find the optimal point for the enzyme, where both the reaction temperature and the solvent concentration result in the highest possible activity,” Seemayer stresses.

In the past, determining this optimal combination of temperature and solvent concentration was a complex process involving many laboratory experiments. Researchers from BASF, acib and the University of Graz have now developed a regression model as an extension of conventional biochemical models. A regression model is a statistical method used to analyze and predict biochemical reactions based on collected scientific data. This model makes it significantly easier to determine the optimal combination. Only a few preliminary lab tests, such as determining the unfolding curve of the enzyme, are necessary. The obtained data are entered into the computer model, which then computes the optimal combination of reaction temperature and solvent concentration for the best-possible enzyme performance.

“This sounds simple, but it considerably improves the efficiency of biocatalytic processes and gives us a new understanding of enzymatic catalysis,” Seemayer says. Owing to the major scientific significance, the researchers were able to publish their findings in one of the most renowned scientific journals, Nature Communications (The full-length publication is available here: www.nature.com/articles/s41467-024-49774-0 ) .

With this new method, different enzymes can be compared more easily with each other, and their performance can be optimized. “This considerably reduces our efforts to find the most suitable conditions for each new production process. We can therefore conclude our research and development work in the laboratory more quickly and thus begin to scale up production faster. This significantly lowers costs and resource consumption, improving the sustainability of biocatalysis,” Seemayer stresses.

At BASF, we create chemistry for a sustainable future. We combine economic success with environmental protection and social responsibility. Around 112,000 employees in the BASF Group contribute to the success of our customers in nearly all sectors and almost every country in the world. Our portfolio comprises six segments: Chemicals, Materials, Industrial Solutions, Surface Technologies, Nutrition & Care and Agricultural Solutions. BASF generated sales of €68.9 billion in 2023. BASF shares are traded on the stock exchange in Frankfurt (BAS) and as American Depositary Receipts (BASFY) in the United States. Further information at www.basf.com .

phd biotechnology in austria

Biotransformation Ludwigshafen

White biotechnology – also known as industrial biotechnology – uses microorganisms and enzymes to produce chemical and biochemical products. The product portfolio of white biotechnology is manifold and comprises basic chemicals, monomers, and many specialty chemicals like vitamins, food and feed supplements, as well as pharmaceutical and agricultural intermediates. Biotechnological processes are often more efficient than classical chemical production and require less raw materials and energy. Usually, they are based on renewable raw material and exhibit a beneficial carbon footprint. Some products like enzymes or complicated actives are only accessible via white biotechnology and cannot be manufactured by chemical synthesis. The first steps in process development for new substances take place in the fermentation laboratory in Ludwigshafen. The production volume is increased step by step. Fermenters with a volume of just a few liters are used. Lab technicians Yvonne Liebner and Thorsten Renz are operating a 5-liter bioreactor. Photo: BASF

White biotechnology – also known as industrial biotechnology – uses microorganisms and enzymes to produce chemical and biochemical products. Bioinformatics plays an important role in the search for the right strains and optimal production processes. Computer algorithms help to find patterns in biological data in order to make the right decisions when choosing experiments. In Ludwigshafen, Dr. Stefan Seemayer, Expert in Protein Engineering and Computational Biology, is supporting, among others, project leader Dr. Barbara Navé in evaluating the big amount of data.

White biotechnology – also known as industrial biotechnology – uses microorganisms and enzymes to produce chemical and biochemical products. Bioinformatics plays an important role in the search for the right strains and optimal production processes. Computer algorithms help to find patterns in biological data in order to make the right decisions when choosing experiments. In Ludwigshafen, Dr. Stefan Seemayer, Expert in Protein Engineering and Computational Biology, is supporting, among others, project leader Dr. Barbara Navé in evaluating the big amount of data. Photo: BASF

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